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Methadone Methadone is a synthetic opioid agonist that belongs to the opioid medication class, used in opioid maintenance therapy. Methadone is also an effective medication for chronic pain. Methadone acts on the brain and nervous system to provide relief against the situation. Methadone is highly addictive and habit-forming even at regular dosages. Using it for the long term can create mental and physical dependence on the medicine. Please never share your medicine with anyone who has a history of drug abuse and addiction. The world health organization has placed Methadone on the list of essential medicines. Being an FDA-approved medicine, buying and selling Methadone without a proper prescription is a criminal offense under the law. Methadone is available as an oral tablet ( 5mg and 10mg ), orally dispersible tablet (40 mg), oral concentrate solution, and oral solution. Methadone is also available as an intravenous (IV) injection that you should take only under a t...